Activities of the Cadham Provincial Laboratory


Media/Quality Assurance

A Level II pathogen is subcultured in a biological Safety Cabinet for Quality Assurance purposesThe Media/Quality Assurance Section is responsible for:

  • Quality assurance of laboratory tests for the Public Health Lab and rural laboratories doing microbiological testing;
  • Quality control of all diagnostic kits, microbial identification systems;
  • Media preparation for rural laboratories;
  • Providing infrastructure and expertise for CPL accreditation surveys; and
  • Assuring laboratory safety.

 


Microbiology

The Microbiology Section is responsible for:

  • Examining cultures for enteric pathogensPublic health laboratory testing and investigation of human bacterial enteric pathogens and food-borne illness investigation e.g., salmonella;
  • Sexually transmitted disease testing, e.g., Chlamydia trachomatis and Neisseria gonorrhea;
  • Screening for mothers and babies at risk for Group B hemolytic streptococcal colonization and infections;
  • Screening protocols for detection of antibiotic resistance including: Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant enterococci;
  • Identification and typing of difficult or unusual organisms;
  • Testing for respiratory organisms such as Mycobacterium tuberculosis, Bordetella pertussis, Legionella species, Corynebacterium diphtheria and Group A Beta hemolytic streptococcus; and
  • Applied research and development of diagnostic methods and organism and toxin identification.

 


Newborn Screening and Public Health Chemistry

The Newborn Screening and Public Health Chemistry section is responsible for:

  • CPL's Newborn Screening and Public Health Chemistry Section uses filter paper blood spots to test all Manitoba newborns for congenital diseasesScreening all newborn babies for over 40 different metabolic and endocrine disorders, including: phenylketonuria (PKU), medium chain acyl-CoA dehydrogenase (MCAD) deficiency, galactosemia, congenital hypothyroidism, cystic fibrosis (CF), biotinidase deficiency, and congenital adrenal hyperplasia;
  • Screening high-risk babies for carnitine palmitoyl transferase type 1 deficiency or glutaric acidemia type 1 deficiency;
  • Screening maternal serum specimens for fetal open neural tube defects and quadruple testing for Downs Syndrome risk assessment; and
  • Providing information, program monitoring, evaluation, referral and patient service

For more information on newborn screening, please click here; practitioners please click here.

arrow What’s New in Newborn Screening in Manitoba September 2011


Serology/Parasitology

The Serology/Parasitology Section is responsible for:

  • Modified acid-fast stain is used for detection of Cryptosporidium,  Cyclospora, and IsosporaSurveillance and diagnosis of Public Health Programs, e.g., prenatal screening for syphilis, hepatitis B and rubella;
  • Monitoring Western Equine Encephalitis and West Nile infections in the environment;
  • Serodiagnostic testing for viral and bacterial diseases, e.g., HIV, Hepatitis, Legionella, Herpes viruses, Lyme disease, Helicobacter pylori;
  • Seroprevalence surveys and vaccine efficacy studies;
  • Quantitative testing of HIV blood to direct therapy;
  • Detection of parasites; and
  • Applied research for serodiagnostic methods.

 


Virus Detection

The Virus Detection Section is responsible for:

  • Technologists examine tissue culture cells daily for evidence of cytopathic effect caused by human virus infectionProvincial viral diagnostic services;
  • Surveillance of respiratory, enteric and sexually transmitted infection of viral etiology;
  • Supplying viral strain information and primary isolates to the Laboratory Centre for Disease Control for national viral surveillance;
  • Monitoring viral isolates to ensure vaccine-preventable diseases are not circulating;
  • Detecting viral infections of immunocompromised persons (HIV-infected, transplant recipients) for treatment,
  • Identifying and monitoring virus outbreaks, including respiratory and enteric;
  • Research and development of new techniques for timely detection of viral agents, typing viral agents to establish source and etiology of outbreaks.

Cadham Provincial Laboratory
750 William Avenue
Winnipeg MB  R3E 3J7
E-mail:  cadham@gov.mb.ca
Phone:  204-945-6123
Fax:      204-786-4770