Manitoba Health

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Tuberculosis (TB) Protocol

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Table of Contents

• Dec. 15, 2011: Addendum to Manitoba Health Tuberculosis (TB) Protocol
  
  

PDF version - 128 pages

1.  Etiology

2.  Case Definitions
      2.1    Laboratory-Confirmed Case
      2.2    Clinically-Confirmed Case
      2.3    New Case
      2.4    Re-Treatment Case
      2.5    Suspect (Probable) Case

3.   Reporting Requirements
       3.1    Physician/Health Care Professional
       3.2    Laboratories
       3.3    Additional Reporting Requirements
              3.3.1    Reporting to the Canadian Tuberculosis Reporting System (CTBRS)
              3.3.2    Reporting to the Canadian Tuberculosis Laboratory Technical Network

4.   Epidemiology
       4.1    Reservoir
       4.2    Transmission
              4.2.1    Mycobacterium tuberculosis (MTB)
              4.2.2    Mycobacterium bovis (M. bovis)
       4.3    Pathogenesis
       4.4    Incubation Period
       4.5    Period of Communicability
       4.6    Host Susceptibility
       4.7    Occurrence
              4.7.1    Global
              4.7.2    Canada
              4.7.3    Manitoba

5.   Clinical Presentation
       5.1    Symptoms
              5.1.1    Symptoms Consistent with Respiratory TB Disease
              5.1.2    Symptoms Suggestive of or Consistent with Nonrespiratory TB Disease

6.   Diagnosis

7.   Key Investigations
      7.1    Transmission Risk Assessment
      7.2    Screening for Co-Infection with HIV      

8.   Control
      8.1    Management of Cases
              8.1.1    Treatment
              8.1.2    Indications for Initiation of Treatment
              8.1.3    Medications Used for Treatment
              8.1.4    Treatment Regimens
              8.1.5    Treatment of Drug-Resistant TB
              8.1.6    Special Considerations in the Treatment of Active TB Disease
      8.2    Management of Contacts
              8.2.1    Prioritization of Contacts for Evaluation
              8.2.2    Testing for Infection with MTB
              8.2.3    Management of Contacts at High Risk for Progression to Active TB Disease

9.   Preventive Measures

10.   Listing of Appendices to the Protocol

• Appendix A:  Collection of Specimens
• Appendix B:  Interferon Gamma Release Assay (IGRA) Testing and Tuberculin Skin Testing (TST)
• Appendix C:  First-Line Anti-Tuberculosis Medication Information
• Appendix D:  Active Tuberculosis Disease: Diagnosis and Treatment
• Appendix E:  Contact Investigation and Outbreak Management
• Appendix F:  Latent Tuberculosis Infection (LTBI): Diagnosis and Treatment
• Appendix G:  Second-Line TB Agents and Their Compatibilities with Lactation
• Appendix H:  Patient Education

11.   Additional Resources
      11.1    For the Public
      11.2    For Health Care Professionals      

12.   References

To reach staff and for general enquiries:

Communicable Disease Control (CDC) Public Health and Primary Health Care Manitoba Health 4th Floor - 300 Carlton St. Winnipeg MB  R3B 3M9  CANADA Phone: (204) 788-6737 Fax: (204) 948-2040